Synonyms

• Anti-CCP
• Anti-citrullinated protein antibodies (ACPA)
• Anti-Cyclic Citrullinated Peptide Ab
• Cyclic Citrullinated Peptide Antibody

Use

The presence of CCP antibodies, when considered in conjunction with other laboratory and clinical findings, is an aid in the diagnosis of rheumatoid arthritis (RA). Approximately 70% of RA patients are positive for anti-CCP IgG, while only 2% of random blood donors and control subjects are positive.